产品货号:
GS4397
中文名称:
重组人BNP
英文名称:
Recombinant Human Brain Natriuretic Peptide
产品规格:
20μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 3.5kDa,a single non-glycosylated polypeptide chain containing 32 amino acids.
储存条件:冷冻(-20℃)
概述
Brain Natriuretic Peptide is encoded by the BNP gene located on the Chr.1 in humans.It is firstly discovered in the porcine brain and given this name,but the protein is mainly expressed in the cardiac ventricles in human body after the excessive stretching of cardiomyocytes.The gene expresses a 134 a.a.sequence which contains a 1-26 a.a.signal peptide and 27-134 a.a.Natriuretic peptides B,and the BNP is the 32 a.a.C-terminus of natriuretic peptides B.The BNP can be cleaved in 16 chains and the rHuBNP is 1-32.BNP acts as a cardiac hormone with a variety of functions including natriuresis,diuresis,vasorelaxation,and inhibition of renin and aldosterone secretion.Additionnaly,it plays a key role in cardiovascular homeostasis,helps restore the bodys salt and water balance and improves heart function.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索:重组人BNP,BNP, Human,Recombinant Human Brain Natriuretic Peptide
储存条件:冷冻(-20℃)
概述
Brain Natriuretic Peptide is encoded by the BNP gene located on the Chr.1 in humans.It is firstly discovered in the porcine brain and given this name,but the protein is mainly expressed in the cardiac ventricles in human body after the excessive stretching of cardiomyocytes.The gene expresses a 134 a.a.sequence which contains a 1-26 a.a.signal peptide and 27-134 a.a.Natriuretic peptides B,and the BNP is the 32 a.a.C-terminus of natriuretic peptides B.The BNP can be cleaved in 16 chains and the rHuBNP is 1-32.BNP acts as a cardiac hormone with a variety of functions including natriuresis,diuresis,vasorelaxation,and inhibition of renin and aldosterone secretion.Additionnaly,it plays a key role in cardiovascular homeostasis,helps restore the bodys salt and water balance and improves heart function.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Data Not Available. |
成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
内毒素 | Less than 1 EU/μg of rHuBNP as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | SPKMVQGSGC FGRKMDRISS SSGLGCKVLR RH |
相关搜索:重组人BNP,BNP, Human,Recombinant Human Brain Natriuretic Peptide